Why You Should Try Liposomal Supplements for Better Sleep

Poor sleep affects everything from your ability to make day-to-day healthy choices to long-term health risks. A bedtime routine and sleep hygiene are essential, and sometimes you need more than lifestyle foundations. For those periods when you need extra help getting deeper and more restorative rest, turn to sleep supplements.

The best supplements for sleep aren't your run-of-the-mill grocery store supplements; instead, choosing high-quality liposomal options will provide optimal absorption and nutrient delivery to support a calm nervous system and healthy sleep cycle. That's exactly what you'll find with Core Med Science.

"The best supplements for sleep aren't your run-of-the-mill grocery store supplements; instead, choosing high-quality liposomal options will provide optimal absorption and nutrient delivery to support a calm nervous system and healthy sleep cycle."

Continue reading as we explore some of the most beneficial supplements for deep sleep, including melatonin, GABA, glutathione, and NAD+, and discover why the best supplements for sleep are liposomal.

Melatonin Supplements for Deep Sleep

Melatonin is the body's natural sleep hormone. In a regular cycle, melatonin levels are low during the day and then increase in the evening and overnight, promoting drowsiness. Oral melatonin is one of the best supplements for sleep, but, like most supplements, the dose, timing, and quality are crucial.

Research suggests that melatonin supplementation not only influences the ability to fall asleep and sleep duration, but it may also help improve the quality of sleep, especially in individuals with metabolic or sleep disorders. (Source 1)

GABA Supplements for Sleep

GABA (gamma-aminobutyric acid) is the primary inhibitory neurotransmitter in the central nervous system, which means when GABA binds to receptors, it inhibits nerve firing and calms the system. Activated GABA receptors also promote sleep, which is the pathway that many sleep-promoting pharmaceuticals target. (Source 2)

However, you can take GABA itself in supplemental form. When compared to a placebo, evidence suggests that GABA supports relaxation and sleep, although more research is needed. (Source 3)

Glutathione Supplements for Sleep

Glutathione is a peptide compound and the body's master antioxidant, well-known for its detoxification and immune benefits. Glutathione may also play a role in sleep. Even short-term sleep deprivation results in lower levels of glutathione, while sleep recovery restores antioxidant levels. Additionally, research suggests that sleep disorders correlate with oxidative stress in the brain. Glutathione can help blunt free radical damage. (Source 4, 5, 6)

NAD+ Supplements for Sleep

NAD+ (nicotinamide adenine dinucleotide) is the active form of vitamin B3 required by all cells (mitochondria in cells) to produce cellular energy. As a supplement, NAD+ provides antioxidant protection, facilitates DNA repair, and offers anti-aging benefits due to improved cellular energy. It's also known for its role in promoting healthy sleep cycles and circadian rhythm. (Source 7)

Research suggests that supplementation with NAD+ improves sleep quality by decreasing inflammation and oxidative stress and enhancing mitochondrial function. (Source 8, 9)

Sleep Well with Core Med Science Liposomal Formulas

The liposomal delivery system encompasses active nutrients in cell-like membranes called liposomes. These liposomes survive the digestive system and are absorbed intact into the body, where they are transported through the blood and delivered to cells that need them. Liposomal supplements are often better tolerated and provide effective results even at lower doses due to enhanced absorption and bioavailability.

"Liposomal supplements are often better tolerated and provide effective results even at lower doses due to enhanced absorption and bioavailability."

Core Med Science Liposomal Sleep Formula Liquid Spray promotes relaxation and deep sleep without morning drowsiness. It contains melatonin, GABA, and glutathione in one formulation. Start with a low dose (1 pump) and titrate up (to a maximum of 6 pumps) before bed to find the most beneficial dose for you.

Combine the sleep formula with Core Med Science Liposomal NAD+ for synergistic benefits. NAD+ can be energizing, so you may want to use it in the morning to boost cellular energy, promote balanced recovery, and support nighttime sleep.

Together, these supplements support overall wellness by promoting better sleep. If you're ready to fall asleep faster, stay asleep longer, and finally feel rested in the morning, add Core Med Science liposomal sleep support to your daily wellness routine.

"If you're ready to fall asleep faster, stay asleep longer, and finally feel rested in the morning, add Core Med Science liposomal sleep support to your daily wellness routine."

References:

1. Fatemeh, G., Sajjad, M., Niloufar, R., Neda, S., Leila, S., & Khadijeh, M. (2022). Effect of melatonin supplementation on sleep quality: a systematic review and meta-analysis of randomized controlled trials. Journal of neurology, 269(1), 205-216. Abstract: https://pubmed.ncbi.nlm.nih.gov/33417003/
2. Gottesmann C. (2002). GABA mechanisms and sleep. Neuroscience, 111(2), 231-239. Abstract: https://pubmed.ncbi.nlm.nih.gov/11983310/
3. Hepsomali, P., Groeger, J. A., Nishihira, J., & Scholey, A. (2020). Effects of Oral Gamma-Aminobutyric Acid (GABA) Administration on Stress and Sleep in Humans: A Systematic Review. Frontiers in neuroscience, 14, 923. Full text: https://pmc.ncbi.nlm.nih.gov/articles/PMC7527439/
4. Trivedi, M. S., Holger, D., Bui, A. T., Craddock, T. J. A., & Tartar, J. L. (2017). Short-term sleep deprivation leads to decreased systemic redox metabolites and altered epigenetic status. PloS one, 12(7), e0181978. Full text: https://pmc.ncbi.nlm.nih.gov/articles/PMC5524320/
5. Everson, C. A., Laatsch, C. D., & Hogg, N. (2005). Antioxidant defense responses to sleep loss and sleep recovery. American journal of physiology. Regulatory, integrative and comparative physiology, 288(2), R374-R383. Abstract: https://pubmed.ncbi.nlm.nih.gov/15472007/
6. Al Lawati, I., Zadjali, F., & Al-Abri, M. A. (2024). Elevated oxidative stress biomarkers in adults with segmented sleep patterns. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 20(6), 959-966. Full text: https://pmc.ncbi.nlm.nih.gov/articles/PMC11145035/
7. Ramsey, K. M., Yoshino, J., Brace, C. S., Abrassart, D., Kobayashi, Y., Marcheva, B., Hong, H. K., Chong, J. L., Buhr, E. D., Lee, C., Takahashi, J. S., Imai, S., & Bass, J. (2009). Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis. Science (New York, N.Y.), 324(5927), 651-654. Full text: https://pmc.ncbi.nlm.nih.gov/articles/PMC2738420/
8. Bushana, P. N., Schmidt, M. A., Rempe, M. J., Sorg, B. A., & Wisor, J. P. (2023). Chronic dietary supplementation with nicotinamide riboside reduces sleep need in the laboratory mouse. Sleep advances : a journal of the Sleep Research Society, 4(1), zpad044. Full text: https://pmc.ncbi.nlm.nih.gov/articles/PMC10752388/
9. Chen, Q., Xiao, J., Lin, Z., Xu, X., & Chen, J. (2024). NAD+ supplement relieved chronic sleep restriction (CSR)-induced microglial proinflammation in vivo and in vitro. Journal of neuroimmunology, 397, 578469. Full text: https://www.sciencedirect.com/science/article/pii/S0165572824001887